The Auspitz sign—pinpoint bleeding when outer scales are removed from psoriatic plaques—is a classic finding in psoriasis, along with several more or less. Synonyms: Auspitz sign, “Phänomen des blutigen Taus” (“phenomenon of bloody dew”). Definition of the phenomenon: The Auspitz phenomenon is the. This page includes the following topics and synonyms: Auspitz Sign.

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Increased proliferatio n of keratinocytes Acanthosis: Generalized erythema Scaling initially in flexural creases.

Auspitz sign is not sensitive or specific for psoriasis.

Other common clinical findings include involvement of the nails e. Find hundreds of Learning Cards covering all clinical subjects Practice answering thousands of USMLE-formatted multiple choice questions in the Qbank Explore concepts in depth with interactive images, videos and charts Fill knowledge gaps with the help of supportive features and an analysis of your progress. Chronic fluid accumulation leads to the formation of intraepidermal vesicles.

Extensor surfaces of extremities e.

Scalp Extensor surfaces of joints kneeselbows Back. Disseminated, plaques with orange-pink scaleshyperkeratosiserythroderma.

Prepare and succeed on your medical exams. The selection is not exhaustive. It appears that JavaScript is disabled in your browser. If first-degree relatives of patients with psoriasis have joint problems, psoriatic arthritis should be considered! Liver and lung toxicity.


Cutaneous variants Plaque psoriasis: Erythemascaling 2—6 days following onset, lesions of underlying diseasepruritus. Clearly demarcated, erythematous plaquesgreasy-looking yellow scales.

Long term use Increased risk of skin cancer Premature aging of the skin. Laboratory tests In case of psoriatic arthritis: Topical medication as combination therapy Add systemic agents as needed methotrexateretinoidcyclosporine Phototherapy. Avoidance of nicotine auspizt alcohol Regular physical activity.

Auspitz’s sign

The mechanism causing the immune response is not yet well understood. Epidermal infiltration by lymphocytes is common. The typical lesions are sharply demarcated, erythematousscaly, pruritic plaqueswhich occur most siign on the extensor surfaces of the knees and elbowsbut may also affect the scalp and back. The diagnosis is based primarily on clinical findings, but may also be confirmed with tests e.

Topical treatment Adverse effects Topical steroids Skin atrophy with chronic use Risk: Medical therapy Mild to moderate psoriasis Moderate to severe psoriasis Severe psoriasis First-line: The disease manifests following exposure to various triggers e. Etanerceptadalimumabinfliximab.

Poorly demarcatedeczemawhite scales, severe xerosis and pruritus. Clearly demarcatederythematous sing with siggn scalingpruritus. Differential diagnosis of scaling Lesion Distribution Psoriasis Clearly demarcatederythematous plaques with silvery scalingpruritus Scalp Extensor surfaces of joints kneeselbows Back Atopic dermatitis Poorly demarcatedausptizwhite scales, severe xerosis and pruritus Extensor surfaces of extremities e.


Ultraviolet light is effective in treating dermatological conditions, as it has antiproliferative effects slowing keratinization and anti-inflammatory effects inducing apoptosis of pathogenic T cells on the skin.

Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition. Rarely correlated with HLA. Psoriasis is associated with depression and a decreased quality of life.

Epidemiological data refers to the US, unless otherwise specified. Skin atrophy with chronic use Risk: Physical stimuli or skin injury e.

Auspitz sign is not sensitive or specific for psoriasis.

Increased risk of other comorbidities Metabolic syndrome Cardiovascular diseases hypertensioncoronary heart diseasemyocardial infarctionstroke Chronic kidney disease References: We list the most important complications.

Mild psoriasis is treated with topical agents such as steroids, whereas moderate to severe disease requires systemic therapy e. Clinical science Psoriasis is a common chronic inflammatory skin disorder affecting individuals with an underlying genetic predisposition.

As psoriasis presents siggn several subtypes, the size, location, and severity of the lesions vary.